{"id":3357,"date":"2022-11-14T17:16:13","date_gmt":"2022-11-14T09:16:13","guid":{"rendered":"https:\/\/epshk.hk\/?p=3357"},"modified":"2022-11-14T17:16:13","modified_gmt":"2022-11-14T09:16:13","slug":"research-shows-the-relationship-between-lower-incidence-ratio-of-covid-19-and-secretory-immunoglobulin-a-in-japanese-people","status":"publish","type":"post","link":"https:\/\/www.epshk.hk\/en\/research-shows-the-relationship-between-lower-incidence-ratio-of-covid-19-and-secretory-immunoglobulin-a-in-japanese-people\/","title":{"rendered":"Research shows the relationship between lower incidence ratio of COVID-19 and secretory immunoglobulin A in Japanese People"},"content":{"rendered":"<p>Dr. Tetsuro Yamamoto, Director of the Research Center of EPS Innovative Medicine Co., Ltd. (Head Office: Shinjuku-ku, Tokyo, Representative Director: Satoshi Okoso), together with Professor Keiichi Tsukinoki of Kanagawa Dental University and Professor Emeritus Hideyo Yamaguchi of Teikyo University, reported the results suggesting that secretory immunoglobulin A is associated with lower incidence of COVID-1 9 in Japan.<\/p>\n<p>&nbsp;<br \/>\n<br \/>\n<strong>\u3010Key points of this research\u3011<\/strong><br \/>\n<br \/>\n\u30fbNoting that as of November 2020, the incidence of COVID-19 is extremely low in Japan\u3000despite the fact that vaccination rates are lower than in other countries.<\/p>\n<p>\u30fbAmong immunoglobulins, we hypothesized that infection with SARS-CoV-2 is inhibited especially by secretory immunoglobulin A (sIgA) secreted from mucous membranes.<\/p>\n<p>\u30fbSaliva samples were collected and examined from all the 180 healthy participants from Japan who had not been exposed to SARS\u2010CoV\u20102. 95 people (or 52.78% of the total) of the individuals were positive for saliva IgA antibodies. It was observed among the study that IgA antibody is associated with a low incidence of covid-19.<\/p>\n<p>&nbsp;<br \/>\n<br \/>\n<strong>\u3010Outline of Paper Publication\u3011<\/strong><br \/>\n<br \/>\nThe results of this research are published in <em>Microbiology and Immunology<\/em> published in August 2022.<\/p>\n<table width=\"588\">\n<tbody>\n<tr>\n<td width=\"76\">Title<\/td>\n<td width=\"513\">Prevalence of saliva immunoglobulin A antibodies\u3000reactive with severe acute respiratory syndrome\u3000coronavirus 2 among Japanese people unexposed to the virus.<\/td>\n<\/tr>\n<tr>\n<td width=\"76\">Authors<\/td>\n<td width=\"513\">Tsukinoki K<sup>(1)<\/sup>, Yamamoto T<sup>(2)<\/sup>, Saito J<sup>(3)<\/sup>, Sakaguchi W<sup>(1)<\/sup>, Iguchi K<sup>(4)<\/sup>, Inoue Y<sup>(5)<\/sup>, et al.<\/td>\n<\/tr>\n<tr>\n<td width=\"76\">Affiliation<\/td>\n<td width=\"513\">(1)Kanagawa Dental University Graduate School of Environmental Pathology<\/p>\n<p>(2)EPS Holdings Co., Ltd.\/ EPS Innovative Medicine Co., Ltd.<\/p>\n<p>(3)Medical Station Clinic<\/p>\n<p>(4)Department of Orthodontics, Kanagawa Dental University<\/p>\n<p>(5)Department of Pediatric Dentistry, Kanagawa Dental University<\/td>\n<\/tr>\n<tr>\n<td width=\"76\">DOI<\/td>\n<td width=\"513\">10.1111\/1348-0421.13011<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong>\u00a0<\/strong><br \/>\n<br \/>\n<strong>\u3010About EPS Innovative Medicine Co., Ltd.\u3011<\/strong><br \/>\n<br \/>\nWe are a core company of EPS Creative Health Technology Group Co., Ltd. in the pharmaceutical discovery business. Our goal is to develop the seeds introduced from academia and the seeds found in our research department, and aims at promoting to Japan and China markets, or to license out to the partner enterprises.<\/p>\n<p>&nbsp;<br \/>\n<br \/>\n<strong>Inquiries regarding this matter<\/strong><\/p>\n<table width=\"100%\">\n<tbody>\n<tr>\n<td>EPS.Innovative Medicine Co., Ltd.<br \/>\n<br \/>\nResearch Center Kazuki Tajima<br \/>\n<br \/>\nE-mail : tajima.kazuki374@eps.co.jp<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>Dr. Tetsuro Yamamoto, Director of the Research Center of EPS Innovative Medicine Co., Ltd. (Head Office: Shinjuku-ku, Tokyo, Representative Director: Satoshi Okoso), together with Professor Keiichi Tsukinoki of Kanagawa Dental University and Professor Emeritus Hideyo Yamaguchi of Teikyo University, reported the results suggesting that secretory immunoglobulin A is associated with lower incidence of COVID-1 9 [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[70],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Research shows the relationship between lower incidence ratio of COVID-19 and secretory immunoglobulin A in Japanese People - EPS Creative Health<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/epshk.hk\/en\/research-shows-the-relationship-between-lower-incidence-ratio-of-covid-19-and-secretory-immunoglobulin-a-in-japanese-people\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Research shows the relationship between lower incidence ratio of COVID-19 and secretory immunoglobulin A in Japanese People - EPS Creative Health\" \/>\n<meta property=\"og:description\" content=\"Dr. Tetsuro Yamamoto, Director of the Research Center of EPS Innovative Medicine Co., Ltd. (Head Office: Shinjuku-ku, Tokyo, Representative Director: Satoshi Okoso), together with Professor Keiichi Tsukinoki of Kanagawa Dental University and Professor Emeritus Hideyo Yamaguchi of Teikyo University, reported the results suggesting that secretory immunoglobulin A is associated with lower incidence of COVID-1 9 [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/epshk.hk\/en\/research-shows-the-relationship-between-lower-incidence-ratio-of-covid-19-and-secretory-immunoglobulin-a-in-japanese-people\/\" \/>\n<meta property=\"og:site_name\" content=\"EPS Creative Health\" \/>\n<meta property=\"article:published_time\" content=\"2022-11-14T09:16:13+00:00\" \/>\n<meta name=\"author\" content=\"user\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"user\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/epshk.hk\/en\/research-shows-the-relationship-between-lower-incidence-ratio-of-covid-19-and-secretory-immunoglobulin-a-in-japanese-people\/\",\"url\":\"https:\/\/epshk.hk\/en\/research-shows-the-relationship-between-lower-incidence-ratio-of-covid-19-and-secretory-immunoglobulin-a-in-japanese-people\/\",\"name\":\"Research shows the relationship between lower incidence ratio of COVID-19 and secretory immunoglobulin A in Japanese People - EPS Creative Health\",\"isPartOf\":{\"@id\":\"https:\/\/www.epshk.hk\/#website\"},\"datePublished\":\"2022-11-14T09:16:13+00:00\",\"dateModified\":\"2022-11-14T09:16:13+00:00\",\"author\":{\"@id\":\"https:\/\/www.epshk.hk\/#\/schema\/person\/761badd7283802b48aae11d0362efb06\"},\"breadcrumb\":{\"@id\":\"https:\/\/epshk.hk\/en\/research-shows-the-relationship-between-lower-incidence-ratio-of-covid-19-and-secretory-immunoglobulin-a-in-japanese-people\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/epshk.hk\/en\/research-shows-the-relationship-between-lower-incidence-ratio-of-covid-19-and-secretory-immunoglobulin-a-in-japanese-people\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/epshk.hk\/en\/research-shows-the-relationship-between-lower-incidence-ratio-of-covid-19-and-secretory-immunoglobulin-a-in-japanese-people\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.epshk.hk\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Research shows the relationship between lower incidence ratio of COVID-19 and secretory immunoglobulin A in Japanese People\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.epshk.hk\/#website\",\"url\":\"https:\/\/www.epshk.hk\/\",\"name\":\"EPS Creative Health\",\"description\":\"Just another WordPress site\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.epshk.hk\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.epshk.hk\/#\/schema\/person\/761badd7283802b48aae11d0362efb06\",\"name\":\"user\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.epshk.hk\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/ff953ef664a0be706733d1bc84dbbf1d?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/ff953ef664a0be706733d1bc84dbbf1d?s=96&d=mm&r=g\",\"caption\":\"user\"},\"url\":\"https:\/\/www.epshk.hk\/en\/author\/user\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Research shows the relationship between lower incidence ratio of COVID-19 and secretory immunoglobulin A in Japanese People - EPS Creative Health","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/epshk.hk\/en\/research-shows-the-relationship-between-lower-incidence-ratio-of-covid-19-and-secretory-immunoglobulin-a-in-japanese-people\/","og_locale":"en_US","og_type":"article","og_title":"Research shows the relationship between lower incidence ratio of COVID-19 and secretory immunoglobulin A in Japanese People - EPS Creative Health","og_description":"Dr. Tetsuro Yamamoto, Director of the Research Center of EPS Innovative Medicine Co., Ltd. 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